AlphaMeld
Workflows · FastAPI

Four scaled workflow types. One API.

Each chains: KG extraction → LLM verification → agentic deep-dive → executive deliverable. Run programmatically. Reproducible at scale.

WF-01

Safety Assessment

On-/off-target liabilities, pathway risk, population signals, competitor safety benchmarking.

WF-02

Indication Discovery / Expansion

From a target, discover and prioritize new indications. KG extraction → LLM verify → agentic deep-dive → biological POC.

WF-03

Target Discovery

From one or more diseases, identify top targets. Endpoint discovery, related-disease grouping, ranking via agents.

WF-04

Hypothesis Generation / Validation

Submit a hypothesis; receive a complete validation package: safety + efficacy, endpoint fit, SoC comparison, full dossier.

Research copilot

ChatAlphaMeld

Conversational entry point to the same substrate. Inside Discovery Navigator, ChatAlphaMeld answers research questions against the knowledge graph and curated agent layer — every answer evidence-linked.

EXAMPLEillustrative
> What targets are most validated for GBA1-PD?
Top three by KG evidence:
· GBA1 — 412 articles, 7 active trials
· LRRK2 — 289 articles, 12 active trials
· GCase activators — 134 articles, 3 readouts
↳ Open in Discovery Navigator → Indication Discovery
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